A blue chip pharmaceutical company in the midlands required a fast-track MDI actives manufacturing vessel for the introduction of a new compound. The vessel required some very novel design features including (ATEX) solvent additions under high pressure, ultra-high shear, high speed mixing (11,000rpm) with an operator exposure level of 1-10ug/m3 and for the manufacturing and homogeneity to occur at -60ºC. The operation is remote within an isolator using the latest wireless video technology and batch data acquisition.
Additionally, accurate dosing was necessary on the discharge and post MDI filling.
Epsilon undertook a detail design order and are pleased to confirm that we are currently manufacturing the vessel which shall be ready for GMP testing with the client on time and within budget.